PURPOSE: cellulose acetate, plasticizers and additivies are mixed, the resultant mixture is subjected to melt spinning and the fibers are treated with an alkali solution to effect partial hydrolysis, thus producing the titled fiber membrane that has a specific average acetylation degree, the inner surface remaining in the form of acetate and good haemocompatibility.
CONSTITUTION: A mixture consisting of cellulose acetate such as cellulose diacetate, plasticizers such as polyethylene glycol and additives is extruded out through the outer nozzles of a double-tube type spinneret and a nitrogen gas is passed through the inner nozzles to effect melt spinning. The resultant hollow fibers are partially hydrolyzed in an alkali solution until the average acetylation degree becomes higher than 10% and the inner surface substantially remains in the form of cellulose acetate. The hollow fiber membrane A shows higher haemocompatibility than the hydrolyzate C of lower acetylation degree and as high as the cellulose acetate membrane B, when they are tested by bringing these fibers into contact with blood by extracorporeal circulation from the carotid artery to the cervical vein in rabbits.
TANEDA NOBUO
MATSUZAWA KIMIHIKO
SOGA KOUJI
| JPS5046921A | 1975-04-26 | |||
| JPS5542420A | 1980-03-25 | |||
| JPS5590615A | 1980-07-09 | |||
| JPS55158318A | 1980-12-09 | |||
| JPS536627A | 1978-01-21 |
Next Patent: PRODUCTION OF CELLULOSE ESTER HOLLOW FIBER WITH SELECTIVE PERMEABILITY