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Title:
置換ビシクロ[1.1.1]ペンタンを調製する方法
Document Type and Number:
Japanese Patent JP6953660
Kind Code:
B2
Abstract:
A process for the preparation of a class of molecules, namely bicyclo[1.1.1]pentanes and derivatives thereof by reaction of [1.1.1]propellane with a variety of reagents under irradiation and/or in the presence of radical initiators to obtain bicyclo[1.1.1]pentanes asymmetrically substituted at position 1 and 3, which are useful as intermediates for the preparation of asymmetrically 1,3-disubstituted bicyclo[1.1.1]pentane derivatives and various physiologically active substances or materials containing these structures.

Inventors:
Yoshikazu Suzuki
Jimenez-Teha, Daniel
Salome, christophe
Fesar, Thomas
Application Number:
JP2018546549A
Publication Date:
October 27, 2021
Filing Date:
March 14, 2017
Export Citation:
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Assignee:
SPIROCHEM AG
International Classes:
C07C5/00; C07C67/343; C07C13/54; C07C67/31; C07C69/753; C07C231/02; C07C235/82; C07C245/14; C07C259/08; C07D263/14
Foreign References:
WO2015110935A1
Other References:
Journal of the American Chemical Society ,1992年,114(2),,P.601-620
Cem. Rev.,1989年,89,P.975-983
Journal of Organic Chemistry ,1988年,53(19),P.4593-4594
,Organic Syntheses,2000年,77,P.249-253
Journal of Organic Chemistry ,1994年,59(11),P.2986-2996
Attorney, Agent or Firm:
Ikeda adult
Junichiro Sakamaki
Masakazu Noda