がんを処置する方法 - X4 Pharmaceuticals, Incorporated

Title:

がんを処置する方法

Document Type and Number:

Japanese Patent JP6958820

Kind Code:

B2

Abstract:

The present invention relates to methods of treating patients with advanced forms of cancer, such as clear cell renal cell carcinoma, in which X4P-001 is administered in order to reduce angiogenic escape that typically occurs with TKI therapy. The methods demonstrate surprising results, including regression of tumor size and cell number, with comparatively little toxicity.

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Inventors:

Part-time job, Robert Dee.
Ragan, Paula Marie
Atkins, Michael Bee.
Myr, James W.
McDermott, David

Application Number:

JP2018549428A

Publication Date:

November 02, 2021

Filing Date:

December 14, 2016

Export Citation:

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Assignee:

X4 Pharmaceuticals, Incorporated
GEORGETOWN UNIVERSITY
Beth Israel Deacones Medical Center, Incorporated

International Classes:

A61K31/4439; A61P13/12; A61P35/00; A61P43/00

Other References:

Leukemia,Vol.25,2011年,pp.1314-1323
Biochemical Pharmacology,Vol.83,2012年,pp.472-479
岡山医学会雑誌,第126巻,2014年,pp.49-54
Cancer Cell International,Vol.7:13,2007年,pp.1-11,doi:10.1186/1475-2867-7-13
CANCER DISCOVERY,Vol.4(1),2014年,pp.22-24
日腎会誌,Vol.44(8),2002年,pp.779-785
Current Oncology Reports,Vol.11,2009年,pp.218-226
Cancer Res.,Vol.65(14),2005年,pp.6178-6188
BLOOD,Vol.107(5),2006年,pp.1761-1767

Attorney, Agent or Firm:

Hidesaku Yamamoto
Natsuki Morishita

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