Title:
【発明の名称】6-[[(アリールおよびヘテロアリール)オキシ]メチル]ナフタレン-2-カルボキシイミドアミド誘導体、それらの製造法およびそれらの治療的適用
Document Type and Number:
Japanese Patent JP2002543176
Kind Code:
A
Abstract:
The invention concerns compounds of general formula (I) wherein: R1 represents either a hydrogen atom, or an amino group, or a C1-C4 alkyl group, or a C1-C6 alkoxycarbonyl group, or a -OH group; R2 represents either a C1-C6 alkyl group, or a phenyl or benzyl group, or a -CH2Q group, wherein Q is a heterocyclic group; R3 and R5 represent independently of each other for example either a hydrogen atom, or a C1-C4 alkyl group, or a -COOH group; R4 represents either a hydrogen atom, or a C1-C4 alkyl group, or a -(CH2)p-COOR8 group; Z represents either a -CH- group, or a nitrogen atom. The invention also concerns the methods of preparation and therapeutic use of said compounds.
Inventors:
Alcofe, Chantal
Bellberg, Patrice
Deluxe, Genevieve
Rattan, Christopher
Lasal, jilberoul
Malar, Sergio
Martin, Valeri
Mason, christine
Mucor, gully
Bellberg, Patrice
Deluxe, Genevieve
Rattan, Christopher
Lasal, jilberoul
Malar, Sergio
Martin, Valeri
Mason, christine
Mucor, gully
Application Number:
JP2000615376A
Publication Date:
December 17, 2002
Filing Date:
April 25, 2000
Export Citation:
Assignee:
SANOFI-SYNTHELABO
International Classes:
A61K31/155; A61K31/17; A61K31/18; A61K31/357; A61K31/36; A61K31/381; A61K31/425; A61K31/426; A61K31/44; A61K31/4406; A61K31/4409; A61K31/455; A61K31/4704; A61P7/00; A61P7/02; A61P7/10; A61P9/00; A61P9/10; A61P31/04; C07B53/00; C07C257/18; C07C275/24; C07C275/26; C07C279/16; C07C311/04; C07C311/07; C07C311/08; C07C311/09; C07C311/13; C07C311/27; C07C311/35; C07C317/28; C07C317/32; C07C323/44; C07D213/34; C07D317/58; C07D213/40; C07D213/68; C07D213/76; C07D213/79; C07D213/80; C07D215/08; C07D215/22; C07D215/227; C07D277/24; C07D277/26; C07D277/28; C07D295/26; C07D319/18; C07D333/20; (IPC1-7): C07C257/18; A61K31/155; A61K31/18; A61K31/357; A61K31/36; A61K31/381; A61K31/426; A61K31/44; A61K31/4406; A61K31/4409; A61K31/455; A61K31/4704; A61P7/02; A61P9/00; C07C275/26; C07C279/16; C07C311/08; C07C311/09; C07C311/13; C07C311/27; C07C311/35; C07C317/32; C07C323/44; C07D213/34; C07D213/40; C07D213/68; C07D213/76; C07D213/80; C07D215/22; C07D277/28; C07D317/58; C07D319/18; C07D333/20
Attorney, Agent or Firm:
Shintaro Nogawa