Title:
【発明の名称】トリプターゼインヒビターとしてのビス-塩基性化合物、それらの調製方法及び医薬組成物としてのそれらの使用
Document Type and Number:
Japanese Patent JP2003514792
Kind Code:
A
Abstract:
The invention relates to bis-basic compounds of the general formula (I): B<1>-Ar<1>-X<1>-Ar<2>-X<2>-A-X<3>-Ar<3>-X<4>-Ar<4>-B<2>, wherein the groups B<1>, B<2>, Ar<1>, Ar<2>, Ar<3>, Ar<4>, X<1>, X<2>, X<3>, X<4> and A have the meaning indicated in the description and the claims. The invention further relates to a method for producing the same and to their use as medicaments, especially as tryptase-inhibiting medicaments.
Inventors:
Andels Skewitz Ralph
Brown christine
Ham liner
Disse Bernd
Jennevine Hans Michael
Speck Georg
Brown christine
Ham liner
Disse Bernd
Jennevine Hans Michael
Speck Georg
Application Number:
JP2001538866A
Publication Date:
April 22, 2003
Filing Date:
November 14, 2000
Export Citation:
Assignee:
Boehringer Ingelheim Pharma Comandito Gezelshaft
International Classes:
C07D295/12; A61K31/137; A61K31/155; A61K31/198; A61K31/216; A61K31/4545; A61K31/495; A61P1/02; A61P1/04; A61P9/10; A61P11/00; A61P11/02; A61P11/06; A61P17/00; A61P17/02; A61P17/04; A61P17/06; A61P19/02; A61P27/14; A61P27/16; A61P29/00; A61P35/00; A61P37/02; A61P37/08; C07C217/58; C07C217/60; C07C257/18; C07C259/18; C07C271/64; C07C271/66; C07D211/26; C07D295/13; (IPC1-7): C07C217/58; A61K31/137; A61K31/155; A61K31/198; A61K31/216; A61K31/4545; A61K31/495; A61P1/02; A61P1/04; A61P9/10; A61P11/00; A61P11/02; A61P11/06; A61P17/00; A61P17/02; A61P17/04; A61P17/06; A61P19/02; A61P27/14; A61P27/16; A61P29/00; A61P35/00; A61P37/02; A61P37/08; C07C217/60; C07C257/18; C07C259/18; C07C271/64; C07D211/26; C07D295/12
Domestic Patent References:
| JP2003507459A | 2003-02-25 | |||
| JP2002502850A | 2002-01-29 | |||
| JP2002502845A | 2002-01-29 | |||
| JP2001509787A | 2001-07-24 |
Foreign References:
| WO1999024395A1 | 1999-05-20 |
Attorney, Agent or Firm:
Minoru Nakamura (9 outside)