Title:
【発明の名称】良性の前立腺過形成の治療に有用な複素環化合物およびそれらの中間体
Document Type and Number:
Japanese Patent JP2001519413
Kind Code:
A
Abstract:
This invention relates a to a series of heterocyclic substituted piperazines of Formula Ipharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention selectively inhibit binding to the alpha-1a adrenergic receptor, a receptor which has been implicated in benign prostatic hyperplasia. As such the compounds are potentially useful in the treatment of this disease.
Inventors:
Hatchings, Reachyard H
Katoya, Halipada
Kuo, Gae-Hong
Ri, Shea Obbing
Murray, William Buoy
Proutei, Kyasarin
Mayayanov, Cynthia
Billani, Frank
Lim, Nelson Sea F
Katoya, Halipada
Kuo, Gae-Hong
Ri, Shea Obbing
Murray, William Buoy
Proutei, Kyasarin
Mayayanov, Cynthia
Billani, Frank
Lim, Nelson Sea F
Application Number:
JP2000515872A
Publication Date:
October 23, 2001
Filing Date:
October 09, 1998
Export Citation:
Assignee:
Ortho-McNeill Pharmacy Incorporated
International Classes:
A61K31/495; A61K31/496; A61K31/506; A61P13/08; A61P43/00; C07D211/76; C07D213/38; C07D261/08; C07D263/32; C07D263/34; C07D277/20; C07D277/28; C07D277/56; C07D295/10; C07D295/108; C07D295/12; C07D295/13; C07D333/20; C07D333/22; C07D333/28; C07D295/08; C07D401/06; C07D409/06; C07D413/06; C07D417/06; (IPC1-7): C07D211/76; A61K31/495; A61K31/496; A61K31/506; A61P13/08; A61P43/00; C07D261/08; C07D263/32; C07D263/34; C07D277/28; C07D277/56; C07D295/08; C07D295/10; C07D295/12; C07D333/20; C07D333/22; C07D401/06; C07D409/06; C07D413/06; C07D417/06
Attorney, Agent or Firm:
Heiyoshi Odashima