Title:
【発明の名称】5-HTレセプターアンタゴニストとしてのインドール誘導体
Document Type and Number:
Japanese Patent JPH10513442
Kind Code:
A
Abstract:
A compound of formula (I) or a salt thereof:wherein:P1 is pyridiyl;P2 is phenyl;A is a bond or a chain of 1 to 5 atoms optionally substituted by C1-6 alkyl;R1 and R2 groups are each independently hydrogen, C1-6alkyl optionally substituted by NR12R13, C2-6alkenyl, C2-6alkynyl, cyano, halogen, CF3, NR12R13, CHO, OCF3, COR14, CH2OR14 or OR14 where R12, R13 and R14 are independently hydrogen or C1-6alkyl;n and m are independently 0, 1 or 2;R3 is hydrogen or C1-6 alkyl;R4 is a group of formula (i):in which:R6 and R7 are independently hydrogen, C1-6 alkyl optionally substituted by one or more fluorine atoms, C1-6alkylthio, C1-6alkoxy or halogen.
Inventors:
Gaster, Laramie Mary
Wyman, Paul Adrian
Keith Raymond, Mulholland
Davids, David Thomas
David Malcolm, Duckworth
Forbes, Ian Thomson
Graham Elgin, Jones
Wyman, Paul Adrian
Keith Raymond, Mulholland
Davids, David Thomas
David Malcolm, Duckworth
Forbes, Ian Thomson
Graham Elgin, Jones
Application Number:
JP52324796A
Publication Date:
December 22, 1998
Filing Date:
January 26, 1996
Export Citation:
Assignee:
SmithKline Beecham Public Limited Company
International Classes:
A61K31/40; A61K31/44; A61K31/4427; A61K31/443; A61K31/4433; A61K31/475; A61K31/495; A61K31/50; A61K31/505; A61P25/00; A61P25/30; A61P43/00; C07D401/12; C07D401/14; C07D403/12; C07D405/14; C07D409/14; C07D413/12; C07D417/14; (IPC1-7): C07D401/12; A61K31/44; A61K31/475; A61K31/495; A61K31/50; A61K31/505; C07D401/14; C07D403/12; C07D405/14; C07D409/14; C07D413/12; C07D417/14
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)