Title:
【発明の名称】オリゴマー化ペプチド-MHC分子複合体
Document Type and Number:
Japanese Patent JP2905170
Kind Code:
B2
Abstract:
Claimed is a peptide or peptide deriv. comprising (A) the amino acid sequence G-M-A-A-L-P-R-L-I-A-F-T-S-E-H-S-H-F-S-L-K-K-G-A-A, (B) E-R-G-K-M-I-P-S-D-L-E-R-R-I-L-E-A-K-Q-K (C) amino acids of the shown sequence shown or a partial region thereof and (D) amino acid sequences showing an equiv. specificity or affinity of binding to MHC mols. as (A) to (C), or (E) a peptide mimetic of (A) to (D). Also claimed are (i) complexes contg. (A) to (D) bound to MHC mols. or derivs. thereof, pref. oligomerised by association of at least two MHC mols. or derivs., (ii) pharmaceutical compsns. (iii) antibodies against (A) to (D), (iv) T-cells reacting with (A) to (D) and (v) T-cells derived from T-cell lines 6/7 or 6/10 (DSM ACC 2172 or 2173).
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Inventors:
YOSEFU ENDORU
PEETAA SUTAARU
UINFURIIDO ARUBAATO
GYUNTAA GERUHARUTO YUNKU
DORORESU JEI SHENDERU
EDOGAA MAINRU
KURAOSU DOONMAIAA
PEETAA SUTAARU
UINFURIIDO ARUBAATO
GYUNTAA GERUHARUTO YUNKU
DORORESU JEI SHENDERU
EDOGAA MAINRU
KURAOSU DOONMAIAA
Application Number:
JP10609897A
Publication Date:
June 14, 1999
Filing Date:
April 23, 1997
Export Citation:
Assignee:
BEERINGAA MANHAIMU GMBH
International Classes:
C07K14/705; A61K31/00; A61K35/14; A61K35/17; A61K38/00; A61K38/08; A61K38/10; A61K38/16; A61K39/395; A61P35/00; A61P37/00; A61P37/06; C07H21/04; C07K7/06; C07K7/08; C07K14/00; C07K14/47; C07K14/52; C07K14/725; C07K14/74; C07K16/00; C07K16/18; C07K16/28; C07K16/42; C07K19/00; C12N5/00; C12N5/07; C12N5/0783; C12N9/88; C12Q1/00; C12Q1/24; G01N33/53; C12R1/91; (IPC1-7): C07K14/74; A61K31/00; A61K38/00; A61K39/395; C07H21/04; C07K7/08; C07K14/47; C07K16/28; C07K19/00; C12N5/06
Domestic Patent References:
| JP3505731A | ||||
| JP6507168A |
Attorney, Agent or Firm:
Yusuke Hiraki (2 outside)