Title:
【発明の名称】改善された薬理学的プロファイルを有するRXRモジュレーター
Document Type and Number:
Japanese Patent JP2003529545
Kind Code:
A
Abstract:
The present invention provides a novel class of RXR modulator compounds that exhibit an improved pharmacologic profile relative to the profile of previously studied RXR modulators, including those that share common structural features with the presently claimed modulators. The present invention also provides synthetic methods for preparing these compounds as well as pharmaceutical compositions incorporating these novel compounds and methods for the therapeutic use of such compounds and pharmaceutical compositions.
Inventors:
Robert jay ardecky
Marcus F. Baume
Amy El Faulkner
Lawrence G. Haman
Todd Kay Jones
Christopher M Mapes
Pierre-Eve Michelle
John S. Tihonas
Anthony W. Thompson
Chen Jun-Hun
Marcus F. Baume
Amy El Faulkner
Lawrence G. Haman
Todd Kay Jones
Christopher M Mapes
Pierre-Eve Michelle
John S. Tihonas
Anthony W. Thompson
Chen Jun-Hun
Application Number:
JP2001523351A
Publication Date:
October 07, 2003
Filing Date:
September 14, 2000
Export Citation:
Assignee:
Ligand Pharmaceuticals, Inc.
International Classes:
C07D249/06; A61K31/192; A61K31/196; A61K31/197; A61K31/341; A61K31/381; A61K31/4192; A61K31/4418; A61P3/04; A61P3/06; A61P3/10; A61P5/48; A61P17/00; A61P17/02; A61P17/04; A61P17/06; A61P17/16; A61P25/02; A61P25/16; A61P25/28; A61P35/00; A61P43/00; C07C59/64; C07C59/68; C07C59/72; C07C229/44; C07D213/55; C07D307/54; C07D333/24; (IPC1-7): C07C59/68; A61K31/192; A61K31/196; A61K31/197; A61K31/341; A61K31/381; A61K31/4192; A61K31/4418; A61P3/04; A61P3/06; A61P3/10; A61P5/48; A61P17/00; A61P17/02; A61P17/04; A61P17/06; A61P17/16; A61P25/02; A61P25/16; A61P25/28; A61P35/00; A61P43/00; C07C59/72; C07C229/44; C07D213/55; C07D249/06; C07D307/54; C07D333/24
Attorney, Agent or Firm:
Kaoru Aoyama (3 people outside)