Title:
【発明の名称】SCAPアンタゴニストである治療剤のスクリーニング
Document Type and Number:
Japanese Patent JP2003504644
Kind Code:
A
Abstract:
The invention relates to a method for screening therapeutic agents, defined as SCAP antagonists, for use in combating diseases associated with elevated lipid levels, said method comprising detecting or assaying the extent or result of transcriptional activity or binding between a control SCAP antagonist and SCAP, in the presence of and absence of said agent. Also claimed are therapeuic agents which are antagonists of SCAP, identified by such a method and their use in combating diseases associated with elevated lipid levels.
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Inventors:
Thierry, Andre, Cashier, Grand-Perret
Marc, Isandu
Marc, Isandu
Application Number:
JP2001510847A
Publication Date:
February 04, 2003
Filing Date:
July 13, 2000
Export Citation:
Assignee:
GLAXO GROUP LIMITED
International Classes:
G01N33/50; A61K45/00; A61P1/18; A61P3/04; A61P3/06; A61P3/10; A61P9/10; A61P43/00; C07D211/22; C07J41/00; C12Q1/02; G01N33/15; G01N33/92; (IPC1-7): G01N33/50; A61K45/00; A61P1/18; A61P3/04; A61P3/06; A61P3/10; A61P9/10; A61P43/00; C12Q1/02; G01N33/15
Attorney, Agent or Firm:
Kenji Yoshitake (3 others)