Title:
【発明の名称】α-ケトヘテロ環類を含有するセリンプロテアーゼ阻害剤
Document Type and Number:
Japanese Patent JP2003505008
Kind Code:
A
Abstract:
The present invention provides a method of inhibiting the enzymatic activity of a serine protease comprising contacting such protease with an inhibitory amount of a compound of formula (I), wherein Z is a serine protease binding moiety; and R1 is an optionally substituted alkyl, alkenyl, cycloalkyl or aryl group.
Inventors:
Giorks, Albert, See.
Spruce, Lyle, W.
Limer, Axel, Etch.
Cellonis, Joan, Si.
Spruce, Lyle, W.
Limer, Axel, Etch.
Cellonis, Joan, Si.
Application Number:
JP2000564992A
Publication Date:
February 12, 2003
Filing Date:
August 17, 1998
Export Citation:
Assignee:
Co-Tech Incorporated
International Classes:
C12N9/99; A61K38/48; A61P7/02; A61P7/04; A61P9/00; A61P9/10; A61P11/00; A61P25/28; A61P31/00; A61P35/00; C07K5/06; C07K5/062; C12N9/00; C12N9/48; C12Q1/37; A61K38/00; (IPC1-7): C12N9/99; A61K38/48; A61P7/02; A61P7/04; A61P9/00; A61P9/10; A61P11/00; A61P25/28; A61P31/00; A61P35/00; C12N9/00; C12N9/48; C12Q1/37
Attorney, Agent or Firm:
Akitoshi Otawa (1 outside)