Title:
【発明の名称】癌および前立腺疾患のための治療としての結合体
Document Type and Number:
Japanese Patent JP2002543163
Kind Code:
A
Abstract:
Peptide conjugates in which cytocidal and cytostatic agents, such as polyamine analogs or naphthoquinones, are conjugated to a polypeptide recognized and cleaved by enzymes such as prostate-specific antigen (PSA) and cathepsin B are provided, as well as compositions comprising these conjugates. Methods of using these conjugates in the treatment of prostate diseases are also provided.
Inventors:
Friedman, Benjamin
Merton, Lawrence Jay.
Merton, Lawrence Jay.
Application Number:
JP2000615058A
Publication Date:
December 17, 2002
Filing Date:
April 27, 2000
Export Citation:
Assignee:
Thrill Biomedical Corporation
International Classes:
A61K31/122; A61K31/133; A61K31/16; A61K31/165; A61K31/22; A61K31/24; A61K31/277; A61K31/343; A61K31/353; A61K31/401; A61K31/409; A61K31/4184; A61K31/473; A61K31/496; A61K31/5377; A61K31/6615; A61K31/7034; A61K38/10; A61K45/00; A61K47/48; A61P15/00; A61P35/00; A61P43/00; C07C45/46; C07C67/343; C07D207/34; C07D219/10; C07D235/18; C07D295/185; C07D307/79; C07D307/92; C07D311/92; C07D317/70; C07D487/22; C07D493/04; C07K5/103; C07K7/06; A61K38/00; (IPC1-7): A61K45/00; A61K31/122; A61K31/133; A61K31/16; A61K31/165; A61K31/22; A61K31/24; A61K31/277; A61K31/343; A61K31/353; A61K31/401; A61K31/409; A61K31/4184; A61K31/473; A61K31/496; A61K31/5377; A61K31/6615; A61K31/7034; A61K47/48; A61P15/00; A61P35/00; A61P43/00
Foreign References:
| WO1998017624A1 | 1998-04-30 | |||
| WO1999003823A2 | 1999-01-28 |
Attorney, Agent or Firm:
Shusaku Yamamoto