Title:
【発明の名称】麻薬性鎮痛剤とベンゾジアゼピンとを組み合わせて非経口投与した後に観察される平均血圧の低下を拮抗させるための医薬品
Document Type and Number:
Japanese Patent JP2620642
Kind Code:
B2
Abstract:
A method of inducing anesthesia or conscious sedation while avoiding serious hypotensive episodes comprising the administration of a parenterally active benzodiazepine in conjunction with an opiate analgesic followed by the parenteral administration of from about 1 to about 3 mg of a long-acting pure narcotic antagonist. The antagonist may be administered during the time interval commencing immediately prior to the procedure and continuing until about 3-5 hours after administration of the opiate-benzodiazepine combination.
Inventors:
Fishman jack
Arnold, John
Shaman, fred
Shawn, Jane
Arnold, John
Shaman, fred
Shawn, Jane
Application Number:
JP50585489A
Publication Date:
June 18, 1997
Filing Date:
April 18, 1989
Export Citation:
Assignee:
Baker Norton Pharmaceuticals, Inc.
International Classes:
A61K31/485; A61K31/515; A61K31/55; A61P9/02; A61P39/02; (IPC1-7): A61K31/515; A61K31/485
Other References:
【文献】Research Communications in Chemical Pathology and Pharmacology第13巻、第4号(1976)P.635
【文献】Modern Pharmcology Ist edition(1982)P.566
【文献】Acta Anaesthesiol Scand.第30号(1986)P.66
【文献】Modern Pharmcology Ist edition(1982)P.566
【文献】Acta Anaesthesiol Scand.第30号(1986)P.66
Attorney, Agent or Firm:
Noriko Murata