Title:
【発明の名称】多孔性粒子を形成するための単純アミノ酸の使用
Document Type and Number:
Japanese Patent JP2003507412
Kind Code:
A
Abstract:
Particles having a tap density of less than 0.4 g/cm 3 include a hydrophobic amino acid or salt thereof and a therapeutic, prophylactic or diagnostic agent or any combination thereof. Preferred particles include a phospholipid, have a median geometric diameter between about 5 and about 30 microns and an aerodynamic diameter between about 1 and about 5 microns. The particles can be formed by spray-drying and are useful for delivery to the pulmonary system.
Inventors:
Baticky, Richard, Pee.
Rip, Michael, M.
Niven, Ralf, W.
Rip, Michael, M.
Niven, Ralf, W.
Application Number:
JP2001518031A
Publication Date:
February 25, 2003
Filing Date:
August 23, 2000
Export Citation:
Assignee:
Advanced Inhalation Research, Inc.
International Classes:
A61K47/18; A61K9/00; A61K9/12; A61K9/16; A61K9/72; A61K47/24; A61K49/00; A61K49/04; A61K51/00; A61P11/00; A61P11/06; (IPC1-7): A61K47/18; A61K9/12; A61K47/24; A61K49/00; A61K49/04; A61K51/00; A61P11/00; A61P11/06
Foreign References:
| WO1998031346A1 | 1998-07-23 | |||
| WO1997044013A1 | 1997-11-27 |
Attorney, Agent or Firm:
Yoshinori Hosoda