Title:
IMMUNOVECTOR WITH CAN BE USED FOR INTRACELLULAR AND INTRANUCLEAR TRANSPORT
Document Type and Number:
Japanese Patent JP2010115202
Kind Code:
A
Abstract:
To provide a coupled product of a biologically active component and an immunovector.
There are provided a product capable of imparting an immunovector with a potency to internalize the biologically active component to eukaryotic cells, and a product in which the immunovector has an affinity for a cell DNA to such an extent that it can transfer the biologically active component into or to an immediate vicinity of the cell nuclei; and the product wherein the immunovector includes an antibody having affinity to a nucleic acid or a fragment of the antibody maintaining the affinity.
Inventors:
AVRAMEAS STRATIS
BUTTIN GERARD
TERNYNCK THERESE
NATO FARIDABANO
AVRAMEAS ALEXANDRE
BUTTIN GERARD
TERNYNCK THERESE
NATO FARIDABANO
AVRAMEAS ALEXANDRE
Application Number:
JP2009288101A
Publication Date:
May 27, 2010
Filing Date:
December 18, 2009
Export Citation:
Assignee:
PASTEUR INSTITUT
UNIV PIERRE & MARIE CURIE PARI
UNIV PIERRE & MARIE CURIE PARI
International Classes:
C12N15/09; A61K31/00; A61K31/70; A61K31/7088; A61K38/00; A61K39/00; A61K39/21; A61K39/395; A61K45/00; A61K47/42; A61K47/48; A61K48/00; A61P31/00; A61P31/18; A61P35/00; A61P43/00; C07K16/00; C07K16/18; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/113; C12P21/08
Foreign References:
| US5428132A | 1995-06-27 |
Attorney, Agent or Firm:
Takehiko Suzue
Kurata Masatoshi
Satoshi Kono
Makoto Nakamura
Yoshihiro Fukuhara
Takashi Mine
Toshio Shirane
Sadao Muramatsu
Kurata Masatoshi
Satoshi Kono
Makoto Nakamura
Yoshihiro Fukuhara
Takashi Mine
Toshio Shirane
Sadao Muramatsu
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