PURPOSE: An inhibitor of blood platelet aggregation promoting dissociation of blood platelet aggregation bulk in organism closely related to diseases such as arteriosclerosis, metastasis of cancer, etc., having excellent preventing effects on thrombosis, containing gliotoxin as an active ingredient.
CONSTITUTION: The titled inhibitor containing glitoxin shown by the formula as an active ingredient. Oral administration, intravenous injection, etc. are preferable as administration method. Even if gliotoxin to be administered is not pure but a crude substance from a filtrate of culture mixture, it has no bad influence on inhibitory effect on blood platelet aggregation. Glitotoxin as the active ingredient can be produced by a microorganism or by chemical synthesis.
WATANUKI MASAAKI
MUTAI MASAHIKO
