Title:
骨形成蛋白の送達のための注入可能なリン酸カルシウム固体ロッドおよびペースト
Document Type and Number:
Japanese Patent JP5392981
Kind Code:
B2
Abstract:
Osteogenic proteins are delivered via an injectable hardenable paste. The formulation comprises a calcium phosphate material, an osteogenic protein, and optional additives and active ingredients such as a bone resorption inhibitor. Methods of making injectable pharmaceutical compositions and methods of using the osteogenic compositions to treat bone defects are also disclosed.
Inventors:
Rebecca Li
Howard Sea Herman
Hyun Kim
Howard Sea Herman
Hyun Kim
Application Number:
JP2006526310A
Publication Date:
January 22, 2014
Filing Date:
September 10, 2004
Export Citation:
Assignee:
Weiss LRC
Etex corporation
Etex corporation
International Classes:
A61K38/00; A61K9/06; A61K9/16; A61K31/663; A61K33/42; A61K38/18; A61K45/00; A61L24/00; A61L27/22; A61L27/42; A61L27/46; A61L27/50; A61P19/10
Other References:
特表2001-514565号公報
特開平10-151188号公報
国際公開第02/100331号
医薬品添加物事典,株式会社薬事日報社,1994年,第31頁及び第125頁
特開平10-151188号公報
国際公開第02/100331号
医薬品添加物事典,株式会社薬事日報社,1994年,第31頁及び第125頁
Attorney, Agent or Firm:
Aoyama Aoi
Takuji Yamada
Michiko Matsutani
Nishino Mitsuru
Mizuhara Masahiro
Mitsuo Tanaka
Kenji Tomita
Takuji Yamada
Michiko Matsutani
Nishino Mitsuru
Mizuhara Masahiro
Mitsuo Tanaka
Kenji Tomita