Title:
INJECTABLE VACCINES AGAINST MULTIPLE MENINGOCOCCAL SEROGROUPS
Document Type and Number:
Japanese Patent JP2016006112
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide improvement in conjugate vaccines against serogroups A, W135 and Y.SOLUTION: There is provided an injectable immunogenic composition. The composition includes capsular saccharides from at least two of serogroups A, C, W135 and Y of Neisseria meningitidis, wherein the capsular saccharides are conjugated to carrier proteins and/or are oligosaccharides, and wherein (i) the composition includes less than 50 μg meningococcal saccharides per dose, and/or (ii) the composition further includes an antigen from one or more of: (a) the serogroup B of N. meningitidis; (b) Haemophilus influenza type B; and/or (c) Streptococcus pneumoniae. Saccharide antigens in the composition are generally conjugated to a carrier.
Inventors:
COSTANTINO PAOLO
Application Number:
JP2015164950A
Publication Date:
January 14, 2016
Filing Date:
August 24, 2015
Export Citation:
Assignee:
NOVARTIS VACCINES & DIAGNOSTIC
International Classes:
A61K39/095; A61K39/09; A61K39/102; A61K39/39; A61P31/04; A61P37/04; C07K14/22
Domestic Patent References:
| JP2002503705A | 2002-02-05 | |||
| JP2002540075A | 2002-11-26 |
Foreign References:
| WO2002058737A2 | 2002-08-01 | |||
| WO2001037863A2 | 2001-05-31 |
Other References:
JPN6010013631; ＲＥＮＮＥＬＳ，Ｍ． ｅｔ ａｌ: 'Ｄｏｓｅ ｅｓｃａｌａｔｉｏｎ， ｓａｆｅｔｙ ａｎｄ ｉｍｍｕｎｏｇｅｎｉｃｉｔｙ ｓｔｕｄｙ ｏｆ ａ ｔｅｔｒａｖａｌｅｎｔ ｍｅｎｉｎｏｇｏｃｏｃｃａｌ ｐｏｌｙｓａｃｃｈａｒｉｄｅ ｄｉｐｈ' Ｐｅｄｉａｔｒ Ｉｎｆｅｃｔ Ｄｉｓ Ｊ Ｖｏｌ．２１， Ｎｏ．１０, 2002, ｐ．９７８-９
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Natsuki Morishita