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Title:
INTERFACE REACTION DETECTION TYPE BIOSENSOR
Document Type and Number:
Japanese Patent JPS6412260
Kind Code:
A
Abstract:

PURPOSE: To measure the physical property of an object to be measured accurately and easily in a short time, by interposing a very thin liquid film of a solution to be measured in a very fine clearance formed between a biologic reaction film and a substrate electrode utilizing an interfacial tension possessed by the solution itself being measured.

CONSTITUTION: A solution O to be measured is dripped with a micropipette P or the like into a space S formed near the circumference of a contact surface between a biologic reaction film A and response surfaces of substrate electrodes B and B and made to diffuse in a very fine clearance C between the film A and the surfaces of the electrodes B and B by an interfacial tension possessed by the solution thereby a very thin liquid film D is interposed between the film A and the response surfaces of the electrodes B and B. This setup enables the detection of electrical signals attributed to a biological reaction diffusing through the film D itself with electrodes B and B as generated in the interface between the film A and the film D by interaction of the film A and the solution O being measured composing the film D thereby measuring a physical property of the solution O.


Inventors:
KOTANI HARUO
TOMITA KATSUHIKO
KOJIMA JUNJI
KONO TAKESHI
Application Number:
JP16919887A
Publication Date:
January 17, 1989
Filing Date:
July 06, 1987
Export Citation:
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Assignee:
HORIBA LTD
International Classes:
G01N27/416; G01N27/07; G01N27/28; G01N27/30; G01N27/327; (IPC1-7): G01N27/07; G01N27/28; G01N27/30; G01N27/46
Domestic Patent References:
JPS56107154A1981-08-25
JPS6150055A1986-03-12
JPS6150054A1986-03-12
Attorney, Agent or Firm:
Hideo Fujimoto