Title:
INTESTINE TREFOIL PROTEIN
Document Type and Number:
Japanese Patent JP2009149687
Kind Code:
A
Abstract:
To provide an intestine trefoil factor and a nucleic acid encoding the intestine trefoil factor, for treating or inhibiting lesion formations.
The intestine trefoil factor (ITF) has resistance to destruction of a digestive tract, and is a medicinal composition applicable to treatment for peptic ulcer disorders, inflammatory bowel diseases, and other insults. A trefoil polypeptide is a polypeptide further containing a marker. A method for detecting an ITF receptor includes a step of bringing a tissue into contact with the trefoil polypeptide marked with a detectable label, and a step of determining the level of the trefoil polypeptide marked with the detectable label and bonded with the tissue.
Inventors:
PODOLSKY DANIEL K
Application Number:
JP2009069639A
Publication Date:
July 09, 2009
Filing Date:
March 23, 2009
Export Citation:
Assignee:
GEN HOSPITAL CORP
International Classes:
A61K38/00; C12N15/02; A61K31/00; A61P1/00; A61P1/04; A61P1/06; A61P11/00; A61P13/02; A61P15/00; A61P17/00; A61P25/08; A61P27/02; A61P35/00; C07K14/47; C07K14/575; C07K16/26; C12N5/10; C12N15/09; C12P21/08; C12Q1/02; G01N33/53
Foreign References:
| WO1992014837A1 | 1992-09-03 | |||
| WO1994017102A1 | 1994-08-04 |
Attorney, Agent or Firm:
Hatsushi Shimizu
Koichi Niimi
Koichi Niimi