【発明の名称】生物学的汚染物質を中和するためのイソアロキサゾール誘導体

Title:

【発明の名称】生物学的汚染物質を中和するためのイソアロキサゾール誘導体

Document Type and Number:

Japanese Patent JP2003512340

Kind Code:

A

Abstract:

Methods are provided for neutralization of microorganisms in fluids or on surfaces. Preferably the fluids contain blood or blood products and comprise biologically active proteins. Preferred methods include the steps of adding an activation-effective amount of a microorganism neutralizer with an isoalloxazine backbone to a fluid and exposing the fluid to a triggering event. Preferred triggering events include light of a suitable wavelength and intensity to activate the microorganism neutralizer or a pH sufficient to activate the microorganism neutralizer. Other fluids, including juices, water and the like, may also be decontaminated by these methods as may surfaces of foods, animal carcasses, wounds, food preparation surfaces and bathing and washing vessel surfaces. Compounds with an isoalloxazine backbone are also provided.

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Inventors:

Platts, Matthew, Stewart
Goodrich, Raymond, Paul, Junior

Application Number:

JP2001531427A

Publication Date:

April 02, 2003

Filing Date:

September 15, 2000

Export Citation:

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Assignee:

Gambro, Incorporated
Goodrich, Raymond, Paul, Junior
Platts, Matthew, Stewart

International Classes:

A01N43/90; A61K31/525; A61K35/14; A61L2/00; A61L2/08; A61L2/10; A61L2/16; A61M1/02; A61M1/28; A61P17/02; C07D475/14; (IPC1-7): A61K35/14; A01N43/90; A61K31/525; A61P17/02; C07D475/14

Domestic Patent References:

JPS61275228A	1986-12-05
JPH1070985A	1998-03-17

Foreign References:

US5095115A	1992-03-10
US3920650A	1975-11-18
US3189598A	1965-06-15
US2111491A	1938-03-15
US2825729A	1958-03-04
US2654735A	1953-10-06

Other References:

JPN6012067191; ＹＡＮＧ，Ｃ．Ｓ．　ｅｔ　ａｌ．: 'Ｍｉｃｒｏｂｉｏｌｏｇｉｃａｌ　ａｎｄ　Ｅｎｚｙｍａｔｉｃ　Ａｓｓａｙｓ　ｏｆ　Ｒｉｂｏｆｌａｖｉｎ　Ａｎａｌｏｇｕｅｓ' Ｊ．　Ｎｕｔｒ．Ｖｏｌ．８４, 1964, ｐ．１６７-１７２
JPN7012005278; ［ｏｎｌｉｎｅ］　ＲＥＧＩＳＴＲＹ　Ｄａｔａｂａｓｅ , 19841116

Attorney, Agent or Firm:

Yoshitaka Sonoda (1 outside)

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