Title:
薬剤活性のあるイソインドリン誘導体
Document Type and Number:
Japanese Patent JP5116201
Kind Code:
B2
Abstract:
Cyclopropyl-N-{2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl] -3-oxoisoindoline-4-yl}-carboxamide, or an acid addition salt thereof, for use in treating an autoimmune disease.
Inventors:
Man, Hong-wa
Muller, George
Muller, George
Application Number:
JP2001536553A
Publication Date:
January 09, 2013
Filing Date:
November 09, 2000
Export Citation:
Assignee:
Celgene Corporation
International Classes:
C07D209/46; A61K31/135; A61K31/16; A61K31/198; A61K31/325; A61K31/4035; A61K31/4178; A61K31/4188; A61K31/4196; A61K31/4245; A61K31/437; A61K31/4745; A61K31/4985; A61P1/00; A61P11/06; A61P11/08; A61P19/02; A61P29/00; A61P31/18; A61P31/22; A61P35/00; A61P37/06; A61P43/00; C07C403/04; C07D209/48; C07D209/49; C07D403/04; C07D403/06; C07D413/04; C07D471/04; C07D487/04
Foreign References:
| WO1997023457A1 | ||||
| WO1998024763A1 | ||||
| WO1997008143A1 | ||||
| WO1999006041A1 | ||||
| WO1998005635A1 | ||||
| WO1997024117A1 |
Other References:
MULLER,G.W. et al.,Structural modifications of thalidomide produce analogs with enhanced tumor necrosis factor inhibito,J Med Chem,1996年,Vol.39, No.17,p.3238-3240
C.G.WERMUTH 編, 長瀬博 監訳,最新 創薬化学 上巻,株式会社 テクノミック,1998年,p.243
C.G.WERMUTH 編, 長瀬博 監訳,最新 創薬化学 上巻,株式会社 テクノミック,1998年,p.243
Attorney, Agent or Firm:
Hiroshi Kobayashi
Eiji Katayama
Norio Omori
Mami Hino
Yasuhito Suzuki
Atsushi Nogami
Etsuko Saito
Eiji Katayama
Norio Omori
Mami Hino
Yasuhito Suzuki
Atsushi Nogami
Etsuko Saito