ISOLATION OF PEPTIDE, PEPTIDE, HYDRIDOMA AND VACCINE COMPOSITION

Title:

ISOLATION OF PEPTIDE, PEPTIDE, HYDRIDOMA AND VACCINE COMPOSITION

Document Type and Number:

Japanese Patent JPS63258598

Kind Code:

A

Abstract:

Peptide fragments isolated from the S. mansoni 28 KD protein by controlled proteolysis. Process for the isolation of a peptide bearing at least one epitope, by proteolysis of the S. mansoni 28 KD protein with V8 protease, the proteolysis then being stopped in order to collect, after heating to 100 DEG C, a peptide whose antigenic activity is verified using the antibodies of a polyclonal serum or monoclonal antibodies. Use in the preparation of vaccinating compositions against S. mansoni.

Inventors:

JIYAN MARUKU BARUURU
REIMONDO PIAASU
JIYAN MARII GURUJIHI
ANDORE KAPURON

Application Number:

JP16766587A

Publication Date:

October 26, 1988

Filing Date:

July 03, 1987

Export Citation:

Click for automatic bibliography generation Help

Assignee:

PASTEUR INSTITUT (FR)
PASTEUR INSTITUT (FR)

International Classes:

A61K39/00; A61K39/015; A61K39/395; C07K14/435; C07K16/18; C12N5/10; C12P21/00; C12N15/02; C12P21/06; C12P21/08; C12R1/91; (IPC1-7): A61K39/015; C07K15/08; C12N5/00; C12N15/00; C12P21/00; C12P21/06; C12R1/91

Attorney, Agent or Firm:

Eiji Saegusa (2 others)

Previous Patent: DIHYDROFOLIC ACID REDUCTASE-SOMATOSTATIN FUSED PROTEIN

Next Patent: PRODUCTION OF ENZYME PROTEIN HYDROLYSATE RICH IN DIPEPTIDE AND TRIPEPTIDE