Title:
KALLIKREIN 7 MODULATORS
Document Type and Number:
Japanese Patent JP2013166768
Kind Code:
A
Abstract:
To provide a crystal structure of serine protease kallikrein 7 and to provide the use of the crystal structure in drug discovery.
The present invention relates to a crystal structure of serine protease kallikrein 7 and to the use of the crystal structure in drug discovery. The present invention also relates to compounds binding specifically to this active site of kallikrein 7.
Inventors:
FLOHR STEFANIE
RANDL STEFAN ANDREAS
OSTERMANN NILS
HASSIEPEN ULRICH
BERST FREDERIC
BODENDORF URSULA
GERHARTZ BERND
MARZINZIK ANDREAS
EHRHARDT CLAUS
MEINGASSNER JOSEF GOTTFRIED
RANDL STEFAN ANDREAS
OSTERMANN NILS
HASSIEPEN ULRICH
BERST FREDERIC
BODENDORF URSULA
GERHARTZ BERND
MARZINZIK ANDREAS
EHRHARDT CLAUS
MEINGASSNER JOSEF GOTTFRIED
Application Number:
JP2013083228A
Publication Date:
August 29, 2013
Filing Date:
April 11, 2013
Export Citation:
Assignee:
NOVARTIS AG
International Classes:
C07D207/16; A61K31/401; A61K31/4025; A61K31/4439; A61K31/445; A61K31/4545; A61K31/472; A61K31/496; A61K31/5377; A61P1/04; A61P1/18; A61P17/00; A61P17/02; A61P17/04; A61P17/06; A61P17/10; A61P17/16; A61P35/00; A61P43/00; C07D211/60; C07D217/26; C07D401/12; C07D405/12; C07D409/12; C12N9/64; C12N15/09
Domestic Patent References:
| JPH11292840A | 1999-10-26 | |||
| JP2003519125A | 2003-06-17 | |||
| JP2006527708A | 2006-12-07 | |||
| JP2007513988A | 2007-05-31 | |||
| JP2006523716A | 2006-10-19 | |||
| JP2005500317A | 2005-01-06 |
Foreign References:
| WO2005092849A1 | 2005-10-06 |
Attorney, Agent or Firm:
Aoyama Aoi
Takuji Yamada
Michiko Matsutani
Mitsutaka Iwasaki
Yasushi Ochiai
Takuji Yamada
Michiko Matsutani
Mitsutaka Iwasaki
Yasushi Ochiai
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