LEVOCETIRIZINE HYDROCHLORIDE-CONTAINING ORALLY DISINTEGRATING TABLET

Title:

LEVOCETIRIZINE HYDROCHLORIDE-CONTAINING ORALLY DISINTEGRATING TABLET

Document Type and Number:

Japanese Patent JP2018108950

Kind Code:

A

Abstract:

PROBLEM TO BE SOLVED: To provide orally disintegrating tablets containing levocetirizine hydrochloride and having excellent oral disintegration, taste, and stability.SOLUTION: The present invention provides an orally disintegrating tablet containing levocetirizine hydrochloride and water-insoluble carbonate. The water-insoluble carbonate includes calcium carbonate and magnesium carbonate. The content of the water-insoluble carbonate may be 0.1 to 20% by weight with respect to the total amount of the orally disintegrating tablet. While the orally disintegrating tablet of the invention is excellent in oral disintegration, the acid stimulus specific to levocetirizine hydrochloride is masked, and the degradation of levocetirizine hydrochloride is suppressed.SELECTED DRAWING: None

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Inventors:

FUKUHARA YASUSHI
ITO KAZUTERU

Application Number:

JP2016256841A

Publication Date:

July 12, 2018

Filing Date:

December 28, 2016

Export Citation:

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Assignee:

SAWAI SEIYAKU KK

International Classes:

A61K31/495; A61K9/20; A61K47/02; A61P37/08; A61P43/00

Domestic Patent References:

JP2002509873A	2002-04-02
JP2012046446A	2012-03-08

Foreign References:

US20060105038A1	2006-05-18
WO2010092828A1	2010-08-19

Attorney, Agent or Firm:

Yoko Tada

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