Title:
An MRI visible hydrophobic copolymer
Document Type and Number:
Japanese Patent JP6207520
Kind Code:
B2
Abstract:
The invention relates to a hydrophobic thermoplastic copolymer which is in particular of use for manufacturing and/or coating medical devices, in particular implantable medical devices, characterized in that it is obtained by copolymerization, and in that it comprises at least one first monomer unit and at least one second monomer unit onto which is grafted a paramagnetic-ion-chelating ligand which can complex with such a paramagnetic ion or a paramagnetic-ion-chelating ligand which is complexed with such a paramagnetic ion, wherein the second monomer unit is grafted in sufficient amount for the copolymer to be visible in magnetic resonance imaging when it is complexed with said paramagnetic ion. The invention also relates to a method for obtaining said hydrophobic thermoplastic copolymer.
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Inventors:
Kudanu, Jean
Darcos, Vincent
El Habu Nouni, Sara
Garrick, Javier
Lumel, laurent
Notlet, Benjamin
Darcos, Vincent
El Habu Nouni, Sara
Garrick, Javier
Lumel, laurent
Notlet, Benjamin
Application Number:
JP2014545443A
Publication Date:
October 04, 2017
Filing Date:
December 07, 2012
Export Citation:
Assignee:
Center National de la Recherche Scientific
International Classes:
C08G63/91; A61K49/12; A61L17/00; A61L27/34; A61L29/08; A61L31/10; C07C247/04; C07F5/00
Domestic Patent References:
JP6511033A | ||||
JP2000507962A | ||||
JP2001507378A | ||||
JP2002516132A | ||||
JP2005269641A | ||||
JP2006503594A | ||||
JP2009073811A | ||||
JP2012532654A |
Foreign References:
WO2008035759A1 | ||||
WO2011004332A1 |
Other References:
XIAOJIE LI,AMPHIPHILIC MULTIARM STAR BLOCK 以下省略,BIOMATERIALS,英国,ELSEVIER SCIENCE PUBLISHERS B.V.,2011年 5月16日,V32 N27,P6595-6605
WEI-LU ZHANG,FABRICATION OF POLYMER-GADOLINIUM (III) COMPLEX NANOMICELLE 以下省略,JOURNAL OF APPLIED POLYMER SCIENCE,米国,JOHN WILEY & SONS INC.,2011年 6月 5日,V120 N5,P2596-2605
WEI-LU ZHANG,FABRICATION OF POLYMER-GADOLINIUM (III) COMPLEX NANOMICELLE 以下省略,JOURNAL OF APPLIED POLYMER SCIENCE,米国,JOHN WILEY & SONS INC.,2011年 6月 5日,V120 N5,P2596-2605
Attorney, Agent or Firm:
Mitsuo Matsui
Hiroshi Murakami
Hiroshi Murakami