Title:
BACE阻害剤として有用な大環状化合物および組成物
Document Type and Number:
Japanese Patent JP2008526912
Kind Code:
A
Abstract:
Macrocyclic compounds of the formula in which R1, R3, V1, V2, X1, X2, Y, Z, Ar, AA and n are as defined in the specification, the number of ring atoms included in the macrocyclic ring being 14, 15, 16, 17 or 18, in free base form or in acid addition salt form, to their preparation, to their use as medicaments and to medicaments comprising them are presented.
Inventors:
Andreas Lerchner
Reiner Machuer
Oliver Jimick
Marina Tintelknot-Bromley
Reiner Machuer
Oliver Jimick
Marina Tintelknot-Bromley
Application Number:
JP2007550760A
Publication Date:
July 24, 2008
Filing Date:
January 13, 2006
Export Citation:
Assignee:
NOVARTIS AG
International Classes:
C07D273/02; A61K31/395; A61P9/00; A61P9/10; A61P25/00; A61P25/28; A61P43/00; C07D245/06; C07D291/08; C07D413/04; C07D413/12; C07D419/12
Domestic Patent References:
| JP2004534064A | 2004-11-11 |
Foreign References:
| WO2002100399A1 | 2002-12-19 | |||
| WO1996016950A1 | 1996-06-06 |
Attorney, Agent or Firm:
Mitsuo Tanaka
Takuji Yamada
Mitsutaka Iwasaki
Aoyama Aoi
Takuji Yamada
Mitsutaka Iwasaki
Aoyama Aoi