Title:
MANUFACTURE OF ALPHA-AMINO-ALPHA-METHYL-CARBOXYLIC ACID AMIDE AND ALPHA-AMINO-ALPHA-CYCLOALKYL-CARBOXYLIC ACID AMIDE
Document Type and Number:
Japanese Patent JPS62178557
Kind Code:
A
Abstract:
The invention relates to a process for the preparation of alpha -amino- alpha -methylcarboxylic acid amides and alpha -amino- alpha -cycloalkylcarboxylic acid amides of the formula: where R1 represents alkyl, alkaryl, aryl, alkenyl, heteroalkyl or heteroaryl, whether or not substituted, R2 is methyl, or forms, together with R1, a cycloalkyl group, by conversion of the corresponding amino nitriles using hydrogen peroxide under basic conditions and is characterized in that the conversion takes place in the presence of ammonia. By preference 2-6 moles hydrogen peroxide and 3-12 moles ammonia are used per mole amino nitrile.
Inventors:
BUIRUHERUMUSU FUUBERUTOUSU YOZ
YOHAN KANPUFUISU
YOHAN KANPUFUISU
Application Number:
JP1150887A
Publication Date:
August 05, 1987
Filing Date:
January 22, 1987
Export Citation:
Assignee:
STAMICARBON
International Classes:
C07B31/00; C07C67/00; C07C231/00; C07C231/06; C07C233/24; C07C237/06; C07C237/14; C07C237/16; C07B43/06; C07C237/20; C07D209/20; C07D521/00; (IPC1-7): C07B43/06; C07C102/08; C07C103/183; C07C103/187; C07C103/19; C07C103/28; C07D209/20; C07D521/00
Attorney, Agent or Firm:
Toshio Yano (1 outside)