To improve processing ability of a medicine separate packaging machine including a medicine splitter by making it possible to deal with various number of splits and amount while suppressing a splitting error without complicating construction.

This powder medicine splitter 10 is provided with two collar formed splitter measure bodies 12A, 12B set in different positions from each other in the horizontal direction to a housing 2. The collar formed splitter measure bodies 12A, 12B have a plurality of measures arranged in a collar form for splitting powder medicine fed from powder medicine feeding equipments 3A, 3B. The number of measures of both collar formed splitter measure bodies 12A, 12B is 24, but the measures of the collar formed splitter measure body 12A are larger in the outer diameter and capacity. The power medicine split by the collar formed splitter measure bodies 12A, 12B are separately packaged by a packaging equipment 5.