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Title:
医薬
Document Type and Number:
Japanese Patent JP6467545
Kind Code:
B2
Abstract:
To provide a medicament for safely treating a patient in need of treatment with pemafibrate, a salt thereof, or a solvate of any of these (hereinafter also referred to as pemafibrate therapy).A medicament for treating a patient in need of pemafibrate therapy, the medicament comprising the step of avoiding or suspending concomitant use of pemafibrate, a salt thereof, or a solvate of any of these as an active ingredient in order to suppress an increase in plasma concentration of pemafibrate when the treatment is combined with a medicament containing an OATP1B inhibitor, or the step of reducing the dose of pemafibrate, a salt thereof, or a solvate of any of these.

Inventors:
Takashi Oshima
Masatoshi Ito
Chisato Nagai
Application Number:
JP2018126038A
Publication Date:
February 13, 2019
Filing Date:
July 02, 2018
Export Citation:
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Assignee:
Kowa Co., Ltd.
International Classes:
A61K31/423; A61K31/496; A61K31/7048; A61K38/13; A61P1/16; A61P3/06; A61P3/10; A61P9/00; A61P9/10; A61P29/00; A61P43/00
Other References:
Kowa Research Institute, Inc.,Drug-Drug Interaction Study in Healthy Adult Volunteers,ClinicalTrials.govに登録された臨床試験「NCT02275962」,2016年 2月 1日,Study Details欄,[retrieved on 2018.07.17], Retrieved from the Internet: Kowa Research Institute, Inc.,Drug-Drug Interaction Study in Healthy Adult Volunteers,ClinicalTrials.govに登録された臨床試験「NCT02275988」,2014年10月27日,Study Details欄,[retrieved on 2018.07.17], Retrieved from the Internet: Kowa Research Institute, Inc.,Drug-Drug Interaction Study in Healthy Adult Volunteers,ClinicalTrials.govに登録された臨床試験「NCT02276001」,2014年10月27日,Study Details欄,[retrieved on 2018.07.17], Retrieved from the Internet: ISHIBASHI S. et al.,Effects of K-877, a novel selective PPARα modulator (SPPARMα), in dyslipidaemic patients: A random,Atherosclerosis,2016年,249,p.36-43,特にABSTRACT
Kowa Research Institute, Inc.,Drug-Drug Interaction Study in Healthy Adult Volunteers,ClinicalTrials.govに登録された臨床試験「NCT02922465」,2016年12月21日,Study Details欄,[retrieved on 2018.07.17], Retrieved from the Internet: 馬場雄介ほか,ペマフィブラートを用いた併用療法: 薬物間相互作用,PROGRESS IN MEDICINE,2017年 9月,37(9),p.1051-1054
原島秀吉,新薬剤学,株式会社南江堂,2011年,改訂第3版,p.268-269
Attorney, Agent or Firm:
Alga Patent Office, a patent business corporation