To provide a method for manufacturing a stamper used for manufacturing microneedle sheets having microneedles of desired shapes.
An original plate 10a including a sheet-like base material 2 and projections 12a is heated at a first predetermined temperature. The projections 12a of the original plate 10a are inserted into the base material 2 in a predetermined period of time. Conical pierced recesses 3a having openings at tips are formed so as to extend from a first surface St of the base material to a second surface Sb opposite to the first surface St by being tapered by a predetermined length. The original plate 10a and the base material 2 are cooled to a second predetermined temperature which is lower than the first predetermined temperature. After cooling the original plate and the base material, the original plate 10a is released from the matrix 2.
MOTOI MASASHI
OKADA TATSUYA
TERADA TOYOJI
TAKADA KANJI
BIOSERENTACK CO LTD
JP2006513811A | 2006-04-27 | |||
JP2009061745A | 2009-03-26 |