METHOD OF MODIFYING THIOL GROUP - UNIV TAIPEI MEDICAL

Title:

METHOD OF MODIFYING THIOL GROUP

Document Type and Number:

Japanese Patent JP2010024174

Kind Code:

A

Abstract:

To provide a method of modifying a thiol group.

The method of modifying a thiol group comprises a step of providing a first substance containing at least one sulfhydryl group; a step of providing a second substance containing at least one thiourea group; and a step of reacting the first compound with the second compound in the presence of a copper (II) ion to form an easily reducible disulfide bond between the sulfhydryl group and the thiourea group in a short time.

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Inventors:

WU YU-WEI
TSAI YU-HUI

Application Number:

JP2008186556A

Publication Date:

February 04, 2010

Filing Date:

July 17, 2008

Export Citation:

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Assignee:

UNIV TAIPEI MEDICAL

International Classes:

C07K1/13; C07B45/06; C07B61/00

Attorney, Agent or Firm:

Hatsushi Shimizu
Toshi Gobe
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Ryuichi Inoue
Masato Ozeki

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