Title:
METHOD FOR PREPARATION OF SUBSTITUTED ARYL LACTIC ACID CONTAINING CYCLODEPSIPEPTIDES WITH 24 RING ATOMS
Document Type and Number:
Japanese Patent JP2008092952
Kind Code:
A
Abstract:
To provide an effective method for preparation of substituted aryl lactic acid containing cyclodepsipeptides.
The invention relates to the new method for the preparation of substituted aryl lactic acid containing cyclodepsipeptides with 24 ring atoms, comprising addition of 4-nitrophnyl lactate to a main culture liquid of Mycelia sterilia, a fungal strain of the Agonomycetales class under an asceptic condition, continuing fermentation and extracting and purifying the culture, or adding substrates such as leucine, lactic acid, ATP, S-adenosyl-L-methionine, 4-nitrophenyl lactate, etc., to the enzymatic preparation isolated from the fungal strain to carry out an in vitro reaction.
Inventors:
JESCHKE PETER
BONSE GERHARD
THIELKING GERHARD
ETZEL WINFRIED
HARDER ACHIM
MENCKE NORBERT
KLEINKAUF HORST
ZOCHER RAINER
IINUMA KATSUHARU
MIYAMOTO KOICHI
BONSE GERHARD
THIELKING GERHARD
ETZEL WINFRIED
HARDER ACHIM
MENCKE NORBERT
KLEINKAUF HORST
ZOCHER RAINER
IINUMA KATSUHARU
MIYAMOTO KOICHI
Application Number:
JP2007271390A
Publication Date:
April 24, 2008
Filing Date:
October 18, 2007
Export Citation:
Assignee:
BAYER AG
International Classes:
C12P21/02; C07D273/00; C07K11/00; C12P1/00; C12P17/14; C12R1/645
Attorney, Agent or Firm:
Heikichi Odashima
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