Title:
ネポジン高含有ギシギシ抽出物の製造方法及びネポジン高含有ギシギシ抽出物
Document Type and Number:
Japanese Patent JP6876679
Kind Code:
B2
Abstract:
An objective of the present invention is to provide a method for producing a nepodin-containing extract containing a high concentration of nepodin with less contaminants present therein thereby being able to be readily carried out on an industrial scale, when compared to the conventional techniques. The objective is solved by A method for producing a nepodin-containing Rumex plant extract, the method comprising the following steps (1) to (5):
(1) a step of subjecting a Rumex plant to an extraction treatment using a nepodin-dissolving solvent to obtain a crude Rumex plant extract;
(2) a step of subjecting the crude Rumex plant extract to a water-adding treatment and/or concentration treatment to obtain a solid crude Rumex plant extract;
(3) a step of subjecting the solid crude Rumex plant extract to a weak alkali treatment to obtain a weak alkali insoluble product;
(4) a step of subjecting the weak alkali insoluble product to a strong alkali treatment to obtain a strong alkali soluble product; and
(5) a step of subjecting the strong alkali soluble product to a neutralization treatment to obtain the nepodin-containing Rumex plant extract.
More Like This:
Inventors:
Yu the Great
Teruya Hayato
Sasaki Kozue
Teruya Toshiaki
Aki Yamano
Sueyoshi Kosuke
Miki Yamada
Teruya Hayato
Sasaki Kozue
Teruya Toshiaki
Aki Yamano
Sueyoshi Kosuke
Miki Yamada
Application Number:
JP2018508585A
Publication Date:
May 26, 2021
Filing Date:
February 21, 2017
Export Citation:
Assignee:
Okinawa Research Center Co., Ltd.
National University Corporation Ryukyu University
National University Corporation Ryukyu University
International Classes:
A61K36/70; A61K31/12; A61P3/04; A61P3/06; A61P3/10; A61P43/00
Domestic Patent References:
| JP53056310A |
Other References:
小谷功 他,生薬の抗真菌性成分の研究(第1報) Rumex japonicus Houtt. ギシギシの根,生薬学雑誌,1977年,Vol.31,No.2,Pages.151-154
Attorney, Agent or Firm:
Toshiaki Morimoto