Title:
METHOD FOR PRODUCING ENAMIDE AND OPTICALLY ACTIVE AMINE DERIVATIVE
Document Type and Number:
Japanese Patent JP2002308842
Kind Code:
A
Abstract:
To provide an industrially advantageous method for producing optically active N-protected amine derivatives useful as the intermediates of agricultural chemicals and pharmaceuticals and enamides very useful as the substrates for producing the same by asymmetric reduction.
The optically active N-protected amino acid derivatives are produced by condensing ketals which can be prepared from an inexpensive raw material with amides or carbamates in the presence of an acid to form enamides, and asymmetrically reducing the enamides with the use of a hydrogenation catalyst to be prepared from a transition metal complex and an optically active ligand.
Inventors:
SUGAWARA MASANOBU
INOUE KENJI
YASUTAKE SEIYA
ILIA DIMITRIEVICH GRIDNEV
AZUMA NATSUKA
IMAMOTO TSUNEO
INOUE KENJI
YASUTAKE SEIYA
ILIA DIMITRIEVICH GRIDNEV
AZUMA NATSUKA
IMAMOTO TSUNEO
Application Number:
JP2001106849A
Publication Date:
October 23, 2002
Filing Date:
April 05, 2001
Export Citation:
Assignee:
KANEGAFUCHI CHEMICAL IND
International Classes:
C07C231/08; C07B53/00; C07B61/00; C07C231/12; C07C231/16; C07C233/05; C07C233/13; (IPC1-7): C07C231/08; C07C231/12; C07C231/16; C07C233/05; C07C233/13
Domestic Patent References:
| JPH08134029A | 1996-05-28 | |||
| JPH08134029A | 1996-05-28 |
Other References:
JPN6010065326, Ｃｈｅｍｉｃａｌ Ａｂｓｔｒａｃｔｓ ４９：３２２１６, 1954
JPN6010065327, Ｃｈｅｍｉｃａｌ Ａｂｓｔｒａｃｔｓ ３０：５７０３３, 1936
JPN6010065327, Ｃｈｅｍｉｃａｌ Ａｂｓｔｒａｃｔｓ ３０：５７０３３, 1936
Attorney, Agent or Firm:
Yasuo Yasutomi (2 outside)