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Patent Searching and Data


Title:
METHOD FOR PRODUCING INFECTIOUS BRONCHITIS VIRUS-LIKE PARTICLE
Document Type and Number:
Japanese Patent JP2009225735
Kind Code:
A
Abstract:

To provide a method for producing a virus-like particle of avian infectious bronchitis virus.

An infectious bronchitis virus-like particle is produced by transducing a plasmid DNA expressing a gene encoding a spike protein of avian infectious bronchitis virus, a gene encoding an envelop protein, a gene encoding a membrane protein and a gene encoding a nucleocapsid protein into a eukaryotic cell, culturing the cell and recovering the object particle from the culture supernatant fluid. Since the virus-like particle is not virus, it is expected to have a function as a safe recombinant component vaccine absolutely free from the risk of producing the disease in chicken.


Inventors:
SATO TAKANORI
FUJISAWA AYUMI
Application Number:
JP2008076170A
Publication Date:
October 08, 2009
Filing Date:
March 24, 2008
Export Citation:
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Assignee:
NIPPON ZEON CO
International Classes:
C12P21/02; C12N15/09; A61K39/00; A61K39/215; A61K48/00; A61P11/00; A61P31/14; A61P43/00; C07K14/165