Title:
MICROBIOLOGICAL PRODUCTION OF 6-HYDROXYNICOTINIC ACID
Document Type and Number:
Japanese Patent JP3220210
Kind Code:
B2
Abstract:
PURPOSE: To obtain a new microorganism using a cyanopyridine as an only one supply source for carbon, nitrogen and energy and capable of simply converting the cyanopyridine into 6-hydroxynicotinic acid useful as an intermediate for dichloronicotinic acid which is a pharmaceutical raw material.
CONSTITUTION: This microorganism grows using 3-cyanopyridine as an only one source for carbon, nitrogen and energy and is further capable of converting the 3-caynopyridine as a substrate into 6-hydroxynicotinic acid, e.g. Acromobacter sp. (DSM6336). The microorganism is prepared by inoculating a sample obtained from, e.g. purifying equipment into a culture medium in a shaking flask, culturing the microorganism using the 3-cyanopyridine as a carbon and energy source, then applying the resultant cultured product to an agar culture medium and carrying out the culture.
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Inventors:
Andreas Keener
Application Number:
JP6055092A
Publication Date:
October 22, 2001
Filing Date:
March 17, 1992
Export Citation:
Assignee:
LONZA LIMITED
International Classes:
C12P17/10; C12P17/12; C12N1/20; C12R1/01; C12R1/025; (IPC1-7): C12N1/20; C12P17/12
Attorney, Agent or Firm:
Takehiko Suzue (4 outside)
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