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Title:
N-PROPARGYL-1-AMINO INDANE, ITS SALT, COMPOSITION AND USE THEREOF
Document Type and Number:
Japanese Patent JP2003160481
Kind Code:
A
Abstract:

To obtain R(+)-N-propargyl-1-aminoindane, its pharmaceutically acceptable salt and a pharmaceutical composition containing the same.

This method for treating patients suffering from Parkinson's disease, a memory disorder, dementia, depression, hyperactive syndrome, an affective illness, a neurodegenerative disease, a neurotoxic injury, brain ischemia, a head trauma injury, a spinal trauma injury, schizophrenia, an attention deficit disorder, multiple sclerosis or withdrawal symptoms comprises using R(+)-N- propargyl-1-aminoindane or its pharmaceutically acceptable salt. This method for preventing nervous damage of patient is provided. Finally this method for producing R(+)-N-propargyl-1-aminoindane, its salt and racemic isomer is provided.


Inventors:
YOUDIM MOUSSA B H
FINBERG JOHN P M
LEVY RUTH
STERLING JEFFREY
LERNER DAVID
BERGER-PASKIN TIRTSAH
YELLIN HAIM
VEINBERG ALEX
Application Number:
JP2002303097A
Publication Date:
June 03, 2003
Filing Date:
October 12, 1994
Export Citation:
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Assignee:
TEVA PHARMA
TECHNION RES & DEV FOUNDATION
International Classes:
A61P9/10; A61K31/135; A61K31/137; A61K31/165; A61K31/195; A61K31/215; A61K45/06; A61P9/08; A61P25/00; A61P25/16; A61P25/18; A61P25/24; A61P25/26; A61P25/28; A61P25/30; A61P25/32; A61P27/02; A61P43/00; C07C211/30; (IPC1-7): A61K31/137; A61P9/10; A61P25/00; A61P25/16; A61P25/18; A61P25/28; A61P25/30; A61P25/32; A61P27/02; A61P43/00
Attorney, Agent or Firm:
Takehiko Suzue (3 outside)