Title:
N-SUBSTITUTED MERCAPTOACYLPROPIONAMIDES
Document Type and Number:
Japanese Patent JPS5724354
Kind Code:
A
Abstract:
Mammalian collagenase is inhibited by compounds having the formula wherein R1 is hydrogen, alkanoyl of 2 to 10 carbon atoms or arylcarbonyl; R2 is 1-pyrrolidinyl, 1-piperidinyl, 4-morpholinyl, 1-piperazinyl, or 4-alkyl-1-piperazinyl; R3 is alkyl of 3 to 8 carbon atoms, cycloalkyl, aryl, or arylalkyl; and n is an integer of 1 to 20.
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Inventors:
JIYOSEFU II SANDEIIN
TAMARA DEJINEKA
TAMARA DEJINEKA
Application Number:
JP8182081A
Publication Date:
February 08, 1982
Filing Date:
May 25, 1981
Export Citation:
Assignee:
SQUIBB & SONS INC
International Classes:
C07D295/12; C07C51/08; C07C51/09; C07C51/367; C07C51/377; C07C67/00; C07C313/00; C07C323/60; C07C325/00; C07C327/32; C07D295/13; C07D317/28; (IPC1-7): C07C149/20; C07C153/07; C07D295/12; C07D317/28
Domestic Patent References:
| JPS476968A | ||||
| JPS5481219A | 1979-06-28 |