To obtain a new amide compound or its salt, in detail, a new amide compound having a pharmacological activity such as 5-hydroxytryptamine (5-HT) antagonism, etc., or its salt.
This compound is represented by general formula (I) R1-A- X-NHCO-R2 (I) (R1 is an aryl group which may contain a substituent group or a heterocyclic group which may contain a substituent group; R2 is a condensed phenyl group which may contain a substituent group, a phenyl group which may contain a substituent group or an indolin-1-yl group substituted with a lower alkylthio group and a trihalo (lower) alkyl group; A is a group of formula (II) or group (III) (R3, R4 and R5 are each a hydrogen atom or a lower alkyl group); X is a phenylene group or a lower alkylene group) or its salt.
GLEN W SPEARS
YAMADA AKIRA
TOMIJIMA MASANORI
KATO MASAYUKI
