Title:
新規蛍光標識化合物
Document Type and Number:
Japanese Patent JP4296097
Kind Code:
B2
Abstract:
It is intended to provide novel labeling reagents characterized by having a group capable of binding to a substance to be labeled (for example, a biological substance, a physiologically active substance, etc.), easily forming a complex together with a rare earth ion, the complex being stable in an aqueous solution, and having a sufficient fluorescence intensity and a long fluorescence life time regardless of buffer types; complexes composed of the above labeling reagent with a rare earth ion; fluorescence labels containing the above complex; a fluorescence assaymethod using the above fluorescent label; etc. Namely, labeling reagents comprising a compound having a 2, 2' :6', 2" -tripyridine skeleton or a 2, 6-dipyrazolopyridine skeleton and having a group capable of binding to a substance to be labeled (for example, a biological substance, a physiologically active substance, etc.) and a group capable of forming a complex together with a rare earth ion; complexes composed of the above labeling reagent with a rare earth ion; fluorescence labels containing the above complex; a fluorescence labeling method using the above complex as a label; and a fluorescence assay method using the above fluorescent label.
Inventors:
Kazuko Matsumoto
Yukari Kageri
King Katsura
Tan Ming
Yukari Kageri
King Katsura
Tan Ming
Application Number:
JP2003575111A
Publication Date:
July 15, 2009
Filing Date:
March 10, 2003
Export Citation:
Assignee:
Kazuko Matsumoto
Tokyo Chemical Industry Co., Ltd.
Tokyo Chemical Industry Co., Ltd.
International Classes:
G01N21/78; C07D213/36; C07D213/38; C07D213/53; C07D401/14; C07D409/14; C07D491/14; C07D498/22; C07F5/00; C09K11/06; C12N15/09; C12Q1/00; C12Q1/68; G01N33/533; G01N33/58
Domestic Patent References:
| JP9241233A | ||||
| JP2000111480A |
Attorney, Agent or Firm:
Norio Saeki