NEW GENE BRACHYURY EXPRESSION BY NUCLEAR INHIBITOR, BENI REGULATING DEVELOPMENT OF MESODERM IN EARLY DEVELOPMENT OF VERTEBRATE

Title:

NEW GENE BRACHYURY EXPRESSION BY NUCLEAR INHIBITOR, BENI REGULATING DEVELOPMENT OF MESODERM IN EARLY DEVELOPMENT OF VERTEBRATE

Document Type and Number:

Japanese Patent JP2007312716

Kind Code:

A

Abstract:

To provide a gene responding to activin A in early development.

The inventor investigated the embryo of Xenopus by using exhaustive microarray method and find out a Unigene code XI. 7756 (named as BENI, Brachyury Expression by Nuclear Inhibitor) as a gene responding to activin A in early development and greatly reducing its expression, and that the gene regulates induction of differentiation of mesoderm while regulating expression of Brachyury which is a specific factor of mesoderm in the nucleus.

Inventors:

ASAJIMA MAKOTO
HONMA MIKIHIRO

Application Number:

JP2006147470A

Publication Date:

December 06, 2007

Filing Date:

May 26, 2006

Export Citation:

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Assignee:

JAPAN SCIENCE & TECH AGENCY

International Classes:

C12N15/09; A61K31/7105; A61K38/00; A61K45/00; A61K48/00; A61P9/00; A61P9/10; A61P13/00; A61P13/02; A61P13/08; A61P13/10; A61P13/12; A61P15/00; A61P15/08; A61P19/00; A61P19/04; A61P19/08; A61P21/00; A61P29/00; A61P35/00; C07K14/46; C12Q1/68; G01N33/15; G01N33/50

Attorney, Agent or Firm:

Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita

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