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Title:
ビタミンD類似体の合成に有用な中間体の新規製造法
Document Type and Number:
Japanese Patent JP4744507
Kind Code:
B2
Abstract:
The present invention relates to novel methods for the preparation of intermediates which are useful in the synthesis of cacipotriol. The present invention relates further to the use of intermediates produced with said methods for making calcipotriol or calcipotriol monohydrate.

Inventors:
Eric Trungoh Hansen
Thomas Peter Sable
Martin John Culverley
Henrik Pedersen
Heinz-Joseph Wilhelm Doisen
Application Number:
JP2007505379A
Publication Date:
August 10, 2011
Filing Date:
March 23, 2005
Export Citation:
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Assignee:
Leo Pharma Actiesl Scab
International Classes:
C07C401/00; C07B37/00; C07B53/00; C07C45/61; C07C49/533; C07D333/72; C07F7/18; C07F9/40; C07F19/00
Domestic Patent References:
JP6256301A
JP7100685B2
JP8325226A
JP2007529433A
Other References:
SOERENSEN,HANNE,BIOCHEMICAL PHARMACOLOGY,1990年,V39 N2,P391-393
Synthesis,2002年,No.12,p.1683-8
CALVERLEY M J,TETRAHEDRON,NL,ELSEVIER SCIENCE PUBLISHERS,1987年,V43 N20,P4609-4619
STEINMEYER ANDREAS,STEROIDS,2001年 3月,V66 N3-5,P257-266
M.A.BLANCHETTE,TETRAHEDRON LETTERS.,NL,ELSEVIER SCIENCE PUBLISHERS,1984年,V25 N21,P2183-2186
Attorney, Agent or Firm:
Aoyama Aoi
Kyousei Tamura
Yasuo Shibata
Kenichi Morizumi
Nagatoshi Shinagawa