To provide a new and epoch-making expression vector available for gene expression regulation, a transformant and a gene expression regulation system using these ones which is more excellent than conventional systems.
Disclosed is a vector which regulates the expression of a target gene in cells, tissues and individuals in which the vector is introduced, wherein the expression vector comprises a recombinant protein gene in which the heavy chain variable region of an antibody is fused with either one of a DNA binding protein or a transcriptional regulatory factor, and a recombinant protein gene in which the light chain variable region of the antibody is fused with a DNA binding protein or a transcriptional regulatory factor which is different one from the transcriptional regulatory factor fused with the heavy chain variable region.
| WO/2000/055178 | INSECT p53 TUMOR SUPPRESSOR GENES AND PROTEINS |
| WO/2003/080655 | A MUTATED IMMUNOGLOBULIN-BINDING PROTEIN |
| JP6306583 | Method for producing products of metabolic pathways |
GION KEIKO
| JPH11500922A | 1999-01-26 | |||
| JP2001520022A | 2001-10-30 |
JPN6013045670; Ｅｕｒ． Ｊ． Ｅｎｄｏｃｒｉｎｏｌ． Ｖｏｌ． １４５, 2001, ｐ． ５１３-５１７
JPN6013045671; Ｊ． Ｂｉｏｓｃｉ． Ｂｉｏｅｎｇ． Ｖｏｌ． ９４， Ｎｏ． ６, 2002, ｐ． ６１４-６１９
Kenji Saito
Mutsuko Nakano
Masahito Hayashi
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