Title:
ナイアシン受容体作動薬、そのような化合物を含んでいる組成物及び治療方法
Document Type and Number:
Japanese Patent JP2008518957
Kind Code:
A
Abstract:
The present invention relates to niacin receptor agonists of formula: (I); as well as pharmaceutically acceptable salts and solvates. The compounds are useful for treating dyslipidemias, and in particular, reducing serum LDL, VLDL and triglycerides, and raising HDL levels. Pharmaceutical compositions and methods of treatment are also included.
Inventors:
Collective, Stephen El
Beresys, Reachyard Tay
Chiyeon
Tata, The A's Earl
Siyun, Hong Si
Marley, Dahlia M
Ton, thiaolin
Free, Jessica El
Chin, Hua-Shang Yang
Beresys, Reachyard Tay
Chiyeon
Tata, The A's Earl
Siyun, Hong Si
Marley, Dahlia M
Ton, thiaolin
Free, Jessica El
Chin, Hua-Shang Yang
Application Number:
JP2007539301A
Publication Date:
June 05, 2008
Filing Date:
October 30, 2005
Export Citation:
Assignee:
MERCK & COMPANY INCOPORATED
International Classes:
C07C233/55; A61K31/196; A61K31/222; A61K31/27; A61K31/277; A61K31/41; A61K31/416; A61K31/423; A61K31/428; A61K31/429; A61K31/437; A61K31/47; A61K31/472; A61K31/517; A61K31/519; A61P3/00; A61P3/06; A61P3/10; A61P9/10; A61P43/00; C07C235/38; C07C235/78; C07C237/20; C07C237/22; C07C255/57; C07C259/10; C07C271/30; C07C271/58; C07C275/42; C07C311/08; C07C311/13; C07D213/80; C07D215/18; C07D215/22; C07D215/38; C07D217/02; C07D217/08; C07D217/24; C07D231/54; C07D231/56; C07D239/84; C07D257/04; C07D261/20; C07D277/82; C07D471/04; C07D487/04; C07D513/04
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura