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Title:
NOVEL ANTI-PD-L1 ANTIBODIES
Document Type and Number:
Japanese Patent JP2022115897
Kind Code:
A
Abstract:
To provide novel anti-PD-L1 antibodies.SOLUTION: The present disclosure provides monoclonal antibodies against protein programmed cell death 1 ligand (PD-L1), which can block the binding of PD-L1 to PD-1, and therefore block the inhibitory function of PD-L1 on PD-1 expressing T cells. The antibodies of disclosure provide very potent agents for the treatment of multiple cancers via modulating human immune function.SELECTED DRAWING: Figure 1

Inventors:
ZHENG YONG
LI JING
CHEN ZHISHENG
Application Number:
JP2022072902A
Publication Date:
August 09, 2022
Filing Date:
April 27, 2022
Export Citation:
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Assignee:
WUXI BIOLOGICS SHANGHAI CO LTD
WUXI BIOLOGICS IRELAND LTD
International Classes:
C12N15/13; A61K39/395; A61P31/12; A61P35/00; A61P35/02; A61P35/04; A61P37/02; C07K16/28; C07K16/46; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/63; G01N33/574
Domestic Patent References:
JP2013511959A2013-04-11
JP2015500207A2015-01-05
Attorney, Agent or Firm:
Shinsuke Umeda
Yuko Matsutoya
Yu Morita
Chisuke Konno
Nobuto Oki