NOVEL HETEROCYCLIC ACETIC ACID DERIVATIVE

Title:

NOVEL HETEROCYCLIC ACETIC ACID DERIVATIVE

Document Type and Number:

Japanese Patent JPS58118564

Kind Code:

A

Abstract:

New compounds of the general formula (I), wherein Y<1> and Y<2> form together a removable carbonyl protecting group and X is a selectively removable esterifying group, are prepared in the way that a compound of the general formula (IV), wherein Y<1> and Y<2> are as defined above, is nitrated and then reduced, the resulting new compound of the general formula (III), wherein Y<1> and Y<2> are as defined above and A stands for nitro group and then for amino group, is converted into a new ester of the general formula (II), wherein Y<1>, Y<2> and X are as defined above, in a manner known per se, and the aminophenyl protecting group of the resulting compound is split off. The new compounds of the general formula (I) can be applied primarily as intermediates in the synthesis of thienamycin or thienamycin analogues.

More Like This:

JP3726121	SYNTHETIC METHOD OF β-LACTAM
JPS5356653	PRODUCTION OF CYCLIC LACTAM
WO/1999/000356	SUBSTITUTED N-[(AMINOIMINOMETHYL OR AMINOMETHYL)PHENYL]PROPYL AMIDES

Inventors:

KARORII REMUPERUTO
GABOORU DORESUSHIYARU
YOZUSEFU FUETSUTAA
GIYURA HORUNYATSUKU
YOZUSEFU NIITSUTORAI
GIYURA SHIMITSUGU
KARORII ZAUERU
CHIBOORU GIZURU
KARUMAN HARUSANI
GIYORUGII FUEKETE
RASUZURO SUZUPORUNII
GIYORUGII HAYOSU

Application Number:

JP23485282A

Publication Date:

July 14, 1983

Filing Date:

December 27, 1982

Export Citation:

Click for automatic bibliography generation Help

Assignee:

RICHTER GEDEON VEGYESZET

International Classes:

C07D205/08; C07D207/277; C07D405/04; C07D477/00; C07D207/26; (IPC1-7): C07D205/08; C07D487/04

Domestic Patent References:

JPS57167964A

1982-10-16

Attorney, Agent or Firm:

Asamura Akira

Previous Patent: MANUFACTURE OF HETEROCYCLIC ACETIC ACID DERIVATIVE

Next Patent: NOVEL HETEROCYCLIC CARBOXYLIC ACID AND MANUFACTURE