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Title:
NUCLEOSIDE PHOSPHORAMIDATE PRODRUGS
Document Type and Number:
Japanese Patent JP2020100617
Kind Code:
A
Abstract:
To provide compounds for treatment of viral infections in mammals.SOLUTION: Disclosed herein are phosphoramidate prodrugs of nucleoside derivative, which are compounds represented by the structure in the figure, stereoisomers thereof, or salts (acid or base addition salts), hydrates, solvates or crystalline forms thereof. Also disclosed are methods of treatment, uses, and processes for preparation utilizing the compounds represented by a formula I.SELECTED DRAWING: None

Inventors:
SOFIA MICHAEL J
DU JINFA
WANG PEIYUAN
NAGARATHNAM DHANAPALAN
Application Number:
JP2019223231A
Publication Date:
July 02, 2020
Filing Date:
December 10, 2019
Export Citation:
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Assignee:
GILEAD PHARMASSET LLC
International Classes:
C07H19/10; A61K31/7068; A61K31/7072; A61K31/7076; A61K31/708; A61P31/12; A61P31/14; A61P31/20; A61P43/00; C07H19/20
Domestic Patent References:
JP5318085B22013-10-16
JP5539419B22014-07-02
JP6377781B22018-08-22
Foreign References:
WO2006121820A12006-11-16
US6475985B12002-11-05
WO2005012327A22005-02-10
WO2006012078A22006-02-02
WO2006063149A12006-06-15
Attorney, Agent or Firm:
Sonoda/Kobayashi Patent Business Corporation