Title:
P-セレクチンに対して選択的に結合するペプチド化合物
Document Type and Number:
Japanese Patent JP4227520
Kind Code:
B2
Abstract:
The present invention relates to compounds which bind selectively to the adhesion molecule human P-selectin, and particularly to such compounds comprising a peptide with an amino acid sequence XAxA3A1A2A1Y, or a functional equivalent of said peptide. In addition, the invention relates to methods for preparing such compounds, to the use of such compounds in therapeutic or diagnostic methods and in pharmaceutical compositions, to nucleic acids encoding for proteinaceous materials comprising the amino acid sequences of said compounds, to gene delivery vehicles comprising such nucleic acids, to binding molecules binding to said compounds, and to a method for determining whether a compound is capable of binding to P-selectin.
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Inventors:
Morenar Thomas Jacobs Maria
Quipel Johann
Fan Berkel Theodorus Josephus Cornelis
Beesen Eric Anna Leonard Dus
Quipel Johann
Fan Berkel Theodorus Josephus Cornelis
Beesen Eric Anna Leonard Dus
Application Number:
JP2003525023A
Publication Date:
February 18, 2009
Filing Date:
August 28, 2002
Export Citation:
Assignee:
Astellas Pharma Yourop Besloten Fennaught Shap
International Classes:
C07K7/06; A61K9/16; C12N15/09; A61K9/20; A61K9/28; A61K9/48; A61K38/00; A61K48/00; A61P1/04; A61P7/00; A61P7/02; A61P9/00; A61P9/10; A61P11/00; A61P25/00; A61P29/00; A61P31/04; A61P35/04; A61P43/00; C07K1/04; C07K7/08; C07K11/00; C07K14/705; C12N15/67; C12N15/85; C12P21/02
Attorney, Agent or Firm:
Sadao Kumakura
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama