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Title:
PHARMACEUTICAL AGENT CONTAINING LOW MOLECULAR WEIGHT POLYSULFATED HYALURONIC ACID DERIVATIVE
Document Type and Number:
Japanese Patent JP2012046511
Kind Code:
A
Abstract:

To provide a polysulfated hyaluronic acid derivative useful for preventing and/or treating allergic diseases.

A low molecular weight polysulfated hyaluronic acid derivative expressed by general formula (IA) or (IB) or a pharmaceutically acceptable salt thereof is provided, wherein n represents a number of 0-15; and R each independently represents H, SO3H or the like.


Inventors:
KAKEHI KAZUAKI
ASAI HIROAKI
HAYASHI NAOHIRO
SHIMIZU SATOSHI
GOTO FUMITAKA
KOGA YASUO
TOMOYASU TAKAHIRO
TAKI TAKAO
KATO YUSUKE
NAKAZATO SATORU
TAKABA JUNJI
AZUMA ATSUSHI
HIRANO CHIKO
IZUMI KAZUNARI
KASHIMOTO NENRYU
SAKAMOTO YOKO
HAYASHI TAKASHI
NISHIDA MASARU
Application Number:
JP2011167126A
Publication Date:
March 08, 2012
Filing Date:
July 29, 2011
Export Citation:
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Assignee:
OTSUKA CHEMICAL CO LTD
OTSUKA PHARMA CO LTD
International Classes:
A61K31/728; A61K31/7016; A61K31/702; A61P11/02; A61P11/06; A61P17/04; A61P27/14; A61P37/08; C07H5/06; C07H7/033; C07H11/00; C08B37/00
Domestic Patent References:
JPH11335288A1999-12-07
JPH11269077A1999-10-05
JPH08277224A1996-10-22
JP2006517185A2006-07-20
JP4884559B22012-02-29
JP5554738B22014-07-23
Foreign References:
WO2004011662A12004-02-05
Other References:
JPN6010070120; Glycobiology 11, 2001, 57-64
JPN6010070121; J. Biol. Chem. 277, 2002, 8882-8889
JPN6010070122; Immunol. Lett. 89, 2003, 99-109
JPN6015013708; Polymer International, 1998, Vol.46, p.225-240
JPN6015013710; Macromol. Symp., 1996, Vol.105, p.1-8
Attorney, Agent or Firm:
Alga Patent Office, a patent business corporation
Toshio Takano
Toshio Nakajima
Masaki Murata
Hiroto Yamamoto